Name | 2-fluoro-3-oxopentanoic acid ethylester |
Synonyms | 6-AMino-hexan-l-ol Voriconazole Impurity 45 Rosuvastatin Impurity 135 ETHYL2-FLUORO-3-OXOPENTANOA Ethyl2-fluoro-3-oxovalerate ETHYL 2-FLUORO-3-OXOPENTANOATE 2-fluoro-3-oxopentanoic acid ethylester 2-FLUORO-3-OXO-PENTANOIC ACID ETHYL ESTER Pentanoic acid, 2-fluoro-3-oxo-, ethyl ester |
CAS | 759-67-1 |
EINECS | 1592732-453-0 |
InChI | InChI=1/C7H11FO3/c1-3-5(9)6(8)7(10)11-4-2/h6H,3-4H2,1-2H3 |
Molecular Formula | C7H11FO3 |
Molar Mass | 162.16 |
Density | 1.077±0.06 g/cm3(Predicted) |
Boling Point | 105-107 °C(Press: 32 Torr) |
pKa | 9.14±0.46(Predicted) |
Storage Condition | -20℃ |
Refractive Index | 1.398 |
Overview | 4-chloro-6-ethyl-5-fluoropyrimidine (IV) is a synthetic voriconazole (V) synthesis of 4-chloro-6-ethyl-5-fluoropyrimidine (IV) requires the use of fluoropropionyl ethyl acetate, voriconazole (Voriconazol, formula (V)) is a new broad-spectrum triazole antifungal agent that inhibits ergosterol biosynthesis by inhibiting cytochrome P450-mediated demethylation of 14 α-sterols in fungi. |
Use | ethyl fluoropropionyl ester may be used in the preparation of 6-ethyl-5-fluoro-4-hydroxy pyrimidine. |
Application | fluoropropionyl ethyl acetate belongs to Ester organic compounds and can be used as pharmaceutical intermediates. |